The standard chemotherapy regimens for Hodgkin’s disease are ABVD
ABVD consists of a 4-drug combination:
Common Side Effects. Common side effects include the following:
- Nausea and vomiting -- drugs known as serotonin antagonists, including ondansetron (Zofran) or granisteron (Kyril), can relieve these side effects in nearly all patients given moderate drugs and most patients who take more powerful drugs.
- Hair loss
- Weight loss
- Fatigue and general aches and pains are called somatic symptoms. Fatigue is especially common after chemotherapy and can even last for years.
- Many women stop menstruating after chemotherapy. The risk for infertility is highest for women with advanced stage Hodgkin’s disease who are treated after age 30. Studies indicate that the risk for infertility is higher with BEACOPP than with ABVD. Researchers are studying whether taking oral contraceptives during chemotherapy can reduce the risk.
- Bone thinning (osteoporosis) may be related to steroid treatments such as prednisone.
- Heart failure may occur with the use of anthracyclines (such as doxorubicin).
- Bleomycin (Blenoxane) is particularly toxic to the lungs.
- Vinblastine may also pose a risk when used in combination with radiation therapy.
Health Guide (February 2013) New York Times